Nerea Irigoyen
Nerea Irigoyen | |
|---|---|
| Born | Nerea Irigoyen Vergara 1981 |
| Nationality | Spanish |
| Alma mater |
|
| Scientific career | |
| Fields | Virology |
| Institutions | |
| Thesis | Analysis of the assembly and maturation processes of the Infectious Bursal Disease Virus capsid (2009) |
| Doctoral advisor | José Francisco Rodríguez Aguirre |
| Website | www |
Nerea Irigoyen Vergara (Zaragoza, Spain, 1981)[1][2] is a virologist specialized in Zika virus. She leads a research group at the Department of Pathology of Cambridge University, in the UK.[3][4]
Career and research[edit]
Nerea Irigoyen studied Pharmacy at the University of Navarra, Spain, and carried out her PhD at CNB-CSIC in Madrid, Spain, under the supervision of José Francisco Rodríguez and José Ruiz Castón.[5] During her predoctoral studies, she spent several months abroad in Trieste, Italy, and Cambridge, UK. After graduating, she moved to the University of Cambridge to work as a Sir Henry Wellcome postdoctoral researcher in Professor Ian Brierley's group in the Virology Division, where she also coordinated a project funded by the Medical Research Council.[6][7] In 2018, she established her own research group, to explore a new technique to explore cells infected by Zika, and other virus like coronavirus and retrovirus.[8] With the start of the COVID-19 pandemic, her group concentrated its efforts on the investigation of SARS-CoV-2, and developed novel pharmacological strategies against this type of infections.[9]
Nerea Irigoyen is one of the founding members of the Society of Spanish Researchers in the UK (SRUK/CERU),[7] an association that promotes communication between Spanish researchers living and working in the United Kingdom, as well as coordinates science communication and policy actions to bridge the gap with Spanish authorities and the general public.
Academic publications (selection)[edit]
- Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection. PLoS Pathogens, 2021.[10]
- Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature, 2021.[11]
- Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 2020.[12]
- An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells. Nature Microbiology, 2019.[13]
References[edit]
- ^ ArainfoNoticias (2021-12-30). "La Comunidad Aspasia ha recuperado y publicado en Wikipedia las biografías de 40 aragonesas". AraInfo · Diario Libre d'Aragón (in Spanish). Retrieved 2022-06-22.
- ^ Aragón, Heraldo de. "Nerea Irigoyen: "Si queremos que la próxima pandemia salga bien, hay que invertir en ciencia ya"". heraldo.es (in Spanish). Retrieved 2022-06-22.
- ^ Irigoyen, Dr Nerea (2019-04-26). "Dr Nerea Irigoyen". www.path.cam.ac.uk. Retrieved 2022-06-20.
- ^ Irigoyen, Nerea; Dinan, Adam M.; Meredith, Luke W.; Goodfellow, Ian; Brierley, Ian; Firth, Andrew E. (2017-03-02). "The translational landscape of Zika virus during infection of mammalian and insect cells": 112904. doi:10.1101/112904. S2CID 90046197.
{{cite journal}}: Cite journal requires|journal=(help) - ^ "Nerea Irigoyen Vergara". Sruk. Retrieved 2022-06-20.
- ^ "Ribosomal frame-shifting and read-through in virus gene expression". Wellcome. Retrieved 2022-06-20.
- ^ a b "The academic career and other science jobs the United Kingdom" (PDF). Fundación Ramón Areces. 27 November 2015. Retrieved 22 June 2022.
- ^ "Spotlight on... Nerea Irigoyen". University of Cambridge School of Biological Sciences. Retrieved 2022-06-20.
- ^ Echavarría-Consuegra, Liliana; Cook, Georgia M.; Busnadiego, Idoia; Lefèvre, Charlotte; Keep, Sarah; Brown, Katherine; Doyle, Nicole; Dowgier, Giulia; Franaszek, Krzysztof; Moore, Nathan A.; Siddell, Stuart G. (2021-06-17). "Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection". PLOS Pathogens. 17 (6): e1009644. doi:10.1371/journal.ppat.1009644. ISSN 1553-7374. PMC 8211288. PMID 34138976.
- ^ Echavarría-Consuegra, Liliana; Cook, Georgia M.; Busnadiego, Idoia; Lefèvre, Charlotte; Keep, Sarah; Brown, Katherine; Doyle, Nicole; Dowgier, Giulia; Franaszek, Krzysztof; Moore, Nathan A.; Siddell, Stuart G. (2021-06-17). Lee, Benhur (ed.). "Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection". PLOS Pathogens. 17 (6): e1009644. doi:10.1371/journal.ppat.1009644. ISSN 1553-7374. PMC 8211288. PMID 34138976.
- ^ Yankova, Eliza; Blackaby, Wesley; Albertella, Mark; Rak, Justyna; De Braekeleer, Etienne; Tsagkogeorga, Georgia; Pilka, Ewa S.; Aspris, Demetrios; Leggate, Dan; Hendrick, Alan G.; Webster, Natalie A. (2021-04-26). "Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia". Nature. 593 (7860): 597–601. Bibcode:2021Natur.593..597Y. doi:10.1038/s41586-021-03536-w. ISSN 1476-4687. PMC 7613134. PMID 33902106. S2CID 233408690.
- ^ Ho, Jessica Sook Yuin; Angel, Matthew; Ma, Yixuan; Sloan, Elizabeth; Wang, Guojun; Martinez-Romero, Carles; Alenquer, Marta; Roudko, Vladimir; Chung, Liliane; Zheng, Simin; Chang, Max (2020-06-25). "Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection". Cell. 181 (7): 1502–1517.e23. doi:10.1016/j.cell.2020.05.035. ISSN 0092-8674. PMC 7323901. PMID 32559462.
- ^ Lulla, Valeria; Dinan, Adam M.; Hosmillo, Myra; Chaudhry, Yasmin; Sherry, Lee; Irigoyen, Nerea; Nayak, Komal M.; Stonehouse, Nicola J.; Zilbauer, Matthias; Goodfellow, Ian; Firth, Andrew E. (2019). "An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells". Nature Microbiology. 4 (2): 280–292. doi:10.1038/s41564-018-0297-1. ISSN 2058-5276. PMC 6443042. PMID 30478287.